SMAD3 Inhibitor, SIS3
Catalogue number:
CAY15945-5 mg
Supplier:
Size:
5 mg
Product is available in:
£493.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1009104-85-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
453.5
Alternative Names:
1-(3,4-dihydro-6,7-dimethoxy-2(1h)-isoquinolinyl)-3-(1-methyl-2-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)-2-propen-1-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective inhibitor of TGF-β and activin signaling that suppresses SMAD3 phosphorylation (IC50 = 3 µM); reduces TGF-β1-induced type 1 procollagen expression and myofibroblast differentiation in normal dermal fibroblasts as well as scleroderma fibroblasts
Storage Temperature:
-20°C
