JNK Inhibitor VIII
Catalogue number:
CAY15946-10 mg
Supplier:
Size:
10 mg
Product is available in:
£249.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
894804-07-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
356.4
Alternative Names:
n-(4-amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxy-benzeneacetamide, c-jun n-terminal kinase inhibitor viii, tcs jnk 6o
- Data sheet: View or download
- MSDS: View or download
Product Description:
An inhibitor of JNK1, JNK2, and JNK3 (Kis= 2, 4, and 52 nM, respectively); selective for JNK1, JNK2, and JNK3 over a panel of 74 kinases (Kis = >720 nM for all); inhibits the phosphorylation of c-Jun in HepG2 cells (EC50 = 920 nM); inhibits NGF-induced neuronal growth and proNGF-induced neurotoxicity of primary mouse superior cervical ganglion neurons at 10 µM; reduces apoptosis induced by GPX1 siRNA knockdown in HeLa cells at 10 µM
Storage Temperature:
-20°C
