£198.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
878141-96-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
337.4
Alternative Names:
4-[2-[[5-methyl-1-(2-naphthalenyl)-1h-pyrazol-3-yl]oxy]ethyl]-morpholine, e-52862
- Data sheet: View or download
- MSDS: View or download
Product Description:
A σ1 receptor antagonist (Ki = 17 nM); selective for σ1 receptors over σ2 receptors (Ki = 9,300 nM), as well as a panel of 170 additional receptors at 1 µM; reduces capsaicin-induced mechanical allodynia, formalin-induced licking and biting behavior, and partial sciatic nerve-ligation induced thermal hyperalgesia in mice (ED50s = 26.3, 43.7, and 18.8 mg/kg, respectively); enhances fentanyl- or loperamide-induced analgesia without affecting gastrointestinal transit in mice
Storage Temperature:
-20°C
