Ataciguat
Catalogue number:
CAY16371-1 mg
Supplier:
Size:
1 mg
Product is available in:
£105.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
254877-67-3
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
576.5
Alternative Names:
5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-n-[4-(4-morpholinylsulfonyl)phenyl]-benzamide, hmr 1766
- Data sheet: View or download
- MSDS: View or download
Product Description:
An anthranilic acid derivative that activates the oxidized (heme-free) form of sGC (EC50 = 0.5-10 µM in purified bovine lung or crude human corpus cavernosum) by binding to the heme pocket and mimicking its function; increases cGMP levels in cultured rat aorta smooth muscle cells and induces vasorelaxation of isolated rat aorta, porcine coronary arteries, and human corpus cavernosum isolates (EC50 = 1-10 µM)
Storage Temperature:
-20°C
