Prostaglandin F2α-1-glyceryl ester
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43042-79-1
≥98% (as a 9:1 mixture of the 2- and 1-glyceryl es
A solution in ethanol
428.6
9α,11α,15s-trihydroxy-prosta-5z,13e-dien-1-oic acid, 1-glyceryl ester, pgf2α-1-glyceryl ester
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- MSDS: View or download
2-Arachidonoyl glycerol (2-AG; Item No. 62160) has been isolated from porcine brain,{4614} and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.{5306} Incubation of 2-AG with COX-2 and specific PGH2 isomerases in cell cultures and isolated enzyme preparations results in prostaglandin glyceryl ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and TXA-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2α-1-glyceryl ester has been investigated,{10555} little is known about its intrinsic biological activity.
-20°C
