Rofecoxib
Catalogue number:
CAY10010260-50 mg
Supplier:
Size:
50 mg
Product is available in:
£112.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
162011-90-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
314.4
Alternative Names:
4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5h)-furanone, mk-966
- Data sheet: View or download
- MSDS: View or download
Product Description:
A NSAID that selectively inhibits COX-2 over COX-1 (IC50s = 0.018 and >15 µM, respectively, for production of PGE2 in CHO cells expressing the recombinant human enzymes); inhibits carrageenan-induced paw edema and hyperalgesia (ID50s = 1.5 and 1.0 mg/kg, respectively), LPS-induced pyresis (ID50 = 0.24 mg/kg), and M. butyricum-induced arthritis (ID50 = 0.74 mg/kg per day) in rats
Storage Temperature:
-20°C