Lopinavir
Catalogue number:
CAY13854-250 mg
Supplier:
Size:
250 mg
Product is available in:
£269.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
192725-17-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
628.8
Alternative Names:
n-[(1s,3s,4s)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-αs-(1-methylethyl)-2-oxo-1(2h)-pyrimidineacetamide, a-157378.0, abt-378
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent HIV-1 protease inhibitor (Ki = 1.3 pM for wild-type enzyme); inhibits the replication of clinical isolates of HIV-1 (EC50s = 5-52 nM); reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s = 26.63 and 26.10 µM, respectively); reduces lung and kidney viral load, bronchointerstitial pneumonia, and pulmonary inflammatory cell infiltration in a marmoset model of MERS-CoV when administered in combination with ritonavir
Storage Temperature:
-20°C