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Lopinavir

Catalogue number:
CAY13854-250 mg
Supplier:
Size:
250 mg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£269.00 Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

192725-17-0

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

628.8

Alternative Names:

n-[(1s,3s,4s)-4-[[2-(2,6-dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-αs-(1-methylethyl)-2-oxo-1(2h)-pyrimidineacetamide, a-157378.0, abt-378

Product Description:

A potent HIV-1 protease inhibitor (Ki = 1.3 pM for wild-type enzyme); inhibits the replication of clinical isolates of HIV-1 (EC50s = 5-52 nM); reduces the infectious virus yield and viral RNA copy numbers in the culture supernatant of Vero E6 cells infected with SARS-CoV-2 (EC50s = 26.63 and 26.10 µM, respectively); reduces lung and kidney viral load, bronchointerstitial pneumonia, and pulmonary inflammatory cell infiltration in a marmoset model of MERS-CoV when administered in combination with ritonavir

Storage Temperature:

-20°C

CAY13854-250 mg: Lopinavir
CAY13854-250 mg: Lopinavir
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