CHIR124
Catalogue number:
CAY16553-5 mg
Supplier:
Size:
5 mg
Product is available in:
£156.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
405168-58-3
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
419.9
Alternative Names:
4-[(3s)-1-azabicyclo[2.2.2]oct-3-ylamino]-3-(1h-benzimidazol-2-yl)-6-chloro-2(1h)-quinolinone
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective, cell-permeable, quinolone-based inhibitor of Chk1 (IC50 = 0.3 nM versus 0.7 µM for Chk1 and Chk2, respectively); inhibits p53-mutant solid tumor cell growth in synergy with topoisomerase I poisons or ionizing radiation, potentiating tumor apoptosis
Storage Temperature:
-20°C
