SD 208
Catalogue number:
CAY16619-1 mg
Supplier:
Size:
1 mg
Product is available in:
£48.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
627536-09-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
352.8
Alternative Names:
2-(5-chloro-2-fluorophenyl)-n-4-pyridinyl-4-pteridinamine, tgf-β ri kinase inhibitor v
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of TGF-βRI kinase (EC50 = 48 nM) that has minimal or no effect at a variety of other kinases; blocks both autocrine and paracrine TGF-β signaling in glioma cells; is orally bioavailable and prevents TGF-β-induced Smad phosphorylation in spleens and brains of mice
Storage Temperature:
-20°C