SB-590885
Catalogue number:
CAY16643-5 mg
Supplier:
Size:
5 mg
Product is available in:
£156.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
405554-55-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
453.5
Alternative Names:
5-[2-[4-[2-(dimethylamino)ethoxy]phenyl]-5-(4-pyridinyl)-1h-imidazol-4-yl]-2,3-dihydro-1h-inden-1-one oxime
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent inhibitor of B-Raf (Kd = 0.3 nM) that less effectively inhibits c-Raf (Ki = 1.72 nM) and has little effect at 46 other kinases; blocks activation of ERK1/2 and anchorage-independent cell proliferation of melanoma cells with either wild type or V600E B-Raf at nanomolar concentrations
Storage Temperature:
-20°C
