RKI-1447
Catalogue number:
CAY16278-50 mg
Supplier:
Size:
50 mg
Product is available in:
£548.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1342278-01-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
326.4
Alternative Names:
n-[(3-hydroxyphenyl)methyl]-n'-[4-(4-pyridinyl)-2-thiazolyl]-urea
- Data sheet: View or download
- MSDS: View or download
Product Description:
A ROCK1 and 2 inhibitor (IC50s = 14.5 and 6.2 nM, respectively) that functions by binding to the ATP binding site of the kinase; suppresses the activation of ROCK substrates MLC-2 and the MLC phosphatase PP1 regulatory subunit MYPT1 at 100 nM in cancer cells
Storage Temperature:
-20°C
