SMI-4a
Catalogue number:
CAY11029-50 mg
Supplier:
Size:
50 mg
Product is available in:
£498.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
438190-29-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
273.2
Alternative Names:
5z-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione
- Data sheet: View or download
- MSDS: View or download
Product Description:
A Pim kinase inhibitor that blocks mTORC1 activity via activation of AMPK, killing a wide range of both myeloid and lymphoid cell lines (with IC50 values ranging from 0.8 to 40 µM); induces G1 phase cell-cycle arrest, dose-dependent induction of p27Kip1, apoptosis through the mitochondrial pathway, and inhibition of the mTORC1 pathway at 10 µM in pre–T-LBL cells
Storage Temperature:
-20°C
