Palonosetron (hydrochloride)
Catalogue number:
CAY16752-50 mg
Supplier:
Size:
50 mg
Product is available in:
£466.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
135729-62-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
332.9
Alternative Names:
2-[(3s)-1-azabicyclo[2.2.2]oct-3-yl]-2,3,3as,4,5,6-hexahydro-1h-benz[de]isoquinolin-1-one, monohydrochloride, rs 25259-197
- Data sheet: View or download
- MSDS: View or download
Product Description:
A 5-HT3 receptor antagonist (Ki = 0.04 nM); selective for 5-HT3 over 5-HT1A, 5-HT1D, 5-HT2A, and 5-HT2C receptors (Kis = ≥15.85 µM for all), as well as a panel of additional neurotransmitter receptors; inhibits 5-HT-induced contraction in isolated guinea pig ileum; inhibits cisplatin-induced emesis in ferrets (ID50 = 1.1 µg/kg, i.v.); inhibits emesis induced by cisplatin, dacarbazine, actinomycin D, and mechlorethamine in dogs (ID50s = 1.9, 4.1, 4.9, and 4.4 µg/kg, respectively)
Storage Temperature:
-20°C
