AZ 960
Catalogue number:
CAY16731-1 mg
Supplier:
Size:
1 mg
Product is available in:
£152.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
905586-69-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
354.4
Alternative Names:
5-fluoro-2-[[(1s)-1-(4-fluorophenyl)ethyl]amino]-6-[(5-methyl-1h-pyrazol-3-yl)amino]-3-pyridinecarbonitrile
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent JAK2 inhibitor (Ki = 0.45 nM in vitro) that decrease STAT3/5 phosphorylation and inhibits cell proliferation (GI50 = 33 nM) in a JAK2 V617F mutated cell line; induces apoptosis in human T cell lymophotropic virus type 1-infected (IC50 = ~1 µM), downregulating phosphorylated forms of JAK2 and Bcl-2 family proteins
Storage Temperature:
-20°C
