Sotrastaurin
Catalogue number:
CAY16726-1 mg
Supplier:
Size:
1 mg
Product is available in:
£64.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
425637-18-9
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
438.5
Alternative Names:
3-(1h-indol-3-yl)-4-[2-(4-methyl-1-piperazinyl)-4-quinazolinyl]-1h-pyrrole-2,5-dione, aeb071
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PKC inhibitor that displays immunosuppressive activity, blocking T cell activation through the disruption of downstream NF-κB signaling; inhibits PKCα, βI, δ, ε, η, and θ with Ki values of 0.95, 0.64, 2.1, 3.2, 1.8, and 0.22 nM, respectively; also inhibits GSK3α and GSK3β (IC50s = 229 and 172 nM, respectively), which activates Wnt/β-catenin signaling and is important for adult stem cell maintenance
Storage Temperature:
-20°C
