AZD 2858
Catalogue number:
CAY16728-5 mg
Supplier:
Size:
5 mg
Product is available in:
£156.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
486424-20-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
453.5
Alternative Names:
3-amino-6-[4-[(4-methyl-1-piperazinyl)sulfonyl]phenyl]-n-3-pyridinyl-2-pyrazinecarboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A GSK3β inhibitor (Ki = 4.9 nM) that crosses the blood brain barrier and inhibits tau phosphorylation (IC50 = 76 nM in vitro); stabilizes β-catenin and increases bone mass (via Wnt activation) in rats after a two-week treatment with a maximum effective oral dose of 20 mg/kg once daily
Storage Temperature:
-20°C
