BMS 833923
Catalogue number:
CAY16240-10 mg
Supplier:
Size:
10 mg
Product is available in:
£142.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1059734-66-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
473.6
Alternative Names:
n-[2-methyl-5-[(methylamino)methyl]phenyl]-4-[(4-phenyl-2-quinazolinyl)amino]-benzamide, xl 139
- Data sheet: View or download
- MSDS: View or download
Product Description:
An orally bioavailable inhibitor of Smo; blocks binding of BODIPY cyclopamine (IC50 = 21 nM) and inhibits Gli activation in cell lines that express wild-type Smo or activated mutant forms of Smo (IC50s = 6-35 nM); inhibits Shh pathway activity and prevents tumor growth in cancer xenograft models
Storage Temperature:
-20°C
