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GNE-0877

Catalogue number:
CAY16251-500 ug
Supplier:
Size:
500 µg
Product is available in:
  • UK
  • Ireland
  • Europe
  • USA
  • Rest of World
£74.00 Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

1374828-69-9

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Weight:

339.3

Alternative Names:

α,α,3-trimethyl-4-[[4-(methylamino)-5-(trifluoromethyl)-2-pyrimidinyl]amino]-1h-pyrazole-1-acetonitrile

Product Description:

A selective, brain-penetrable LRRK2 inhibitor (Ki = 0.7 nM); inhibits LRRK2 Ser1292 autophosphorylation in BAC transgenic mice expressing human LRRK2 protein with the G2019S Parkinson’s disease mutation (IC50 = 3 nM in vivo)

Storage Temperature:

-20°C

CAY16251-500 ug: GNE-0877
CAY16251-500 ug: GNE-0877
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