£181.00
Estimated delivery Tue 30 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
182431-12-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
693.7
Alternative Names:
n-(2,2,2-trifluoroethyl)-9-[4-[4-[[[4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-1-piperidinyl]butyl]-9h-fluorene-9-carboxamide, aegr 773, bms 201038
- Data sheet: View or download
- MSDS: View or download
Product Description:
An MTTP inhibitor (IC50 = 0.5 nM in a triglyceride transfer assay); inhibits ApoB secretion in HepG2 cells (EC50 = 0.8 nM); inhibits triglyceride secretion in fasted rats (ED50 = 0.19 mg/kg, p.o.); reduces total plasma cholesterol levels in hamsters (ED50 = 2.4 mg/kg); decreases plasma cholesterol and triglyceride levels in the WHHL rabbit model of homozygous familial hypercholesterolemia at 10 mg/kg
Storage Temperature:
-20°C
