£169.00
Estimated delivery Tue 30 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1403254-99-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
572.7
Alternative Names:
n-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-5-[ethyl(tetrahydro-2h-pyran-4-yl)amino]-4-methyl-4'-(4-morpholinylmethyl)-[1,1'-biphenyl]-3-carboxamide, tazemetostat
- Data sheet: View or download
- MSDS: View or download
Product Description:
An orally bioavailable, selective inhibitor of EZH2 (Ki = 2.5 nM); blocks H3K27 trimethylation in both wild-type and mutant lymphoma cells (IC50s range from 2-90 nM); induces apoptosis and differentiation specifically in SMARCB1-deleted malignant rhabdoid tumor cells and promotes their regression in xenograft-bearing mice
Storage Temperature:
-20°C
