£863.00
Estimated delivery Tue 30 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1221485-83-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
425.4
Alternative Names:
2-[(2,4-difluorophenyl)amino]-7-[(2r)-2,3-dihydroxypropoxy]-10,11-dihydro-5h-dibenzo[a,d]cyclohepten-5-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
An ATP-competitive inhibitor of p38 MAPK isoform p38α (IC50s = 5 nM) and p38β (97% inhibition at 1 µM); has little effect on a range of other kinases, including p38γ and p38δ; blocks the phosphorylation of HSP27, a p38 MAPK substrate, in response to stimulation with anisomycin in HeLa cells (IC50 = 25 nM)
Storage Temperature:
-20°C
