£1101.00
Estimated delivery Fri 9 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
571203-78-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
547.1
Alternative Names:
2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3h)-quinazolinone
- Data sheet: View or download
- MSDS: View or download
Product Description:
A ferroptosis inducer; induces ferroptotic cell death in vitro, an effect that can be blocked by ferroptosis inhibitors; inhibits cystine uptake by the system xc- cystine-glutamate transporter in HT-1080 fibrosarcoma and Calu-1 lung carcinoma cells at 5 µM; inhibits glutamate release via the cystine-glutamate transporter in an enzyme-coupled fluorescence assay (EC50 = 1.2 µM); selectively induces cell death in cells expressing the SV40 small T oncoprotein and oncogenic Ras (IC50s = 1.25-5 µg/ml)
Storage Temperature:
-20°C
