Trimipramine (maleate)
Catalogue number:
CAY15921-1 g
Supplier:
Size:
1 g
Product is available in:
£45.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
521-78-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
410.5
Alternative Names:
10,11-dihydro-n,n,β-trimethyl-5h-dibenz[b,f]azepine-5-propanamine, (2z)-2-butenedioate
- Data sheet: View or download
- MSDS: View or download
Product Description:
A tricyclic antidepressant; selectively binds to SERT over NET and DAT (Kds = 149, 2,450, and 3,780 nM, respectively) and acts as a histamine H1 receptor antagonist (Ki = 0.02 µM) that is selective for histamine H1 over H2, H3, and H4 receptors (Kis = 0.04, >100, and 43.6 µM, respectively); binds to muscarinic acetylcholine and α1- and α2-adrenergic receptors (Kds = 58, 24, and 580 nM, respectively), as well as dopamine D1 and D2 receptors and 5-HT receptor subtypes 5-HT1C and 5-HT2 (Kis = 346.7, 57.5, 537, and 19.5 nM, respectively); reduces immobility time in the forced swim test in rats at 10 mg/kg
Storage Temperature:
-20°C
