GDC-0623
Catalogue number:
CAY19479-25 mg
Supplier:
Size:
25 mg
Product is available in:
£392.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1168091-68-6
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
456.2
Alternative Names:
5-[(2-fluoro-4-iodophenyl)amino]-n-(2-hydroxyethoxy)-imidazo[1,5-a]pyridine-6-carboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent, ATP-uncompetitive inhibitor of MEK1 (Ki = 0.13 nM in the presence of ATP); inhibits the proliferation of A375 BRAF(V600E) and HCT116 KRAS(G13D)-mutant cancer cell lines (EC50 = 7 and 42 nM, respectively); upregulates pro-apoptotic BIM
Storage Temperature:
-20°C
