Compound E
Catalogue number:
CAY15579-500 ug
Supplier:
Size:
500 µg
Product is available in:
£245.00
Estimated delivery Wed 7 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
209986-17-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
490.5
Alternative Names:
n-[(1s)-2-[[(3s)-2,3-dihydro-1-methyl-2-oxo-5-phenyl-1h-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluoro-benzeneacetamide, γ-secretase inhibitor xxi
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent, cell-permeable, and selective inhibitor of γ-secretase, blocking the cleavage of both APP and Notch CTFs with IC50 values of ~0.3 nM; induces neuronal differentiation, impairs ovarian folliculogenesis, and suppresses thymocyte development by preventing Notch activation by γ-secretase
Storage Temperature:
-20°C