BIX 02565
Catalogue number:
CAY19183-500 ug
Supplier:
Size:
500 µg
Product is available in:
£60.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1311367-27-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
458.6
Alternative Names:
(5r)-n-[1-[3-(dimethylamino)propyl]-1h-benzimidazol-2-yl]-2,3,4,5-tetrahydro-5-methyl-1-oxo-1h-[1,4]diazepino[1,2-a]indole-8-carboxamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent RSK2 inhibitor (IC50 = 1.1 nM) that also demonstrates off-target binding at multiple adrenergic receptor subtypes that are important for vascular tone and cardiac function (IC50s = 0.052-1.820 µM for adrenergic α1A, α1B, α1D, α2A, β2, and imidazoline I2 receptors); also inhibits LRRK2 and PRKD1 (IC50s = 16 and 35 nM, respectively)
Storage Temperature:
-20°C
