BI-9564
Catalogue number:
CAY17897-10 mg
Supplier:
Size:
10 mg
Product is available in:
£278.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1883429-22-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
353.4
Alternative Names:
4-(4-((dimethylamino)methyl)-2,5-dimethoxyphenyl)-2-methyl-2,7-naphthyridin-1(2h)-one
- Data sheet: View or download
- MSDS: View or download
Product Description:
A selective inhibitor of BRD9 and BRD7 bromodomains (Kds = 14.1 and 239 nM; IC50s = 75 nM and 3.4 µM; ~90% inhibition in FRAP assay at 0.1 µM and 1 µM, respectively); inhibits the growth of EOL-1 AML cells both in vitro (EC50 = 800 nM) and in a disseminated mouse model of AML (180 mg/kg/day)
Storage Temperature:
-20°C
