SB-334867
Catalogue number:
CAY19145-25 mg
Supplier:
Size:
25 mg
Product is available in:
£445.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
792173-99-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
319.3
Alternative Names:
n-(2-methyl-6-benzoxazolyl)-n'-1,5-naphthyridin-4-yl-urea
- Data sheet: View or download
- MSDS: View or download
Product Description:
An OX1R antagonist (KB = 39.8 nM); selective for OX1R over OX2R (KB = 1,995.3 nM); reduces food intake and increases resting duration in rats, as well as inhibits orexin-A-induced increases in food intake, at 30 mg/kg; inhibits orexin-A-induced increases in grooming time in rats at 10 mg/kg; increases the seizure threshold in both the MEST and 6 Hz psychomotor seizure test in mice at 30 and 3 mg/kg, respectively; reduces morphine-induced analgesia in the formalin test in rats at 0.5-50 nmol, i.c.v.; reduces acquisition and consolidation of spatial memory in the Morris water maze in rats when administered to the dentate gyrus at 1.5-6 µg
Storage Temperature:
-20°C
