Inauhzin
Catalogue number:
CAY19771-5 mg
Supplier:
Size:
5 mg
Product is available in:
£182.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
309271-94-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
469.6
Alternative Names:
1-(10h-phenothiazin-10-yl)-2-(5h-1,2,4-triazino[5,6-b]indol-3-ylthio)-1-butanone
- Data sheet: View or download
- MSDS: View or download
Product Description:
A cell-permeable, selective SIRT1 inhibitor (IC50 = 0.7-2 µM) that reactivates p53 by inhibiting SIRT1 deacetylation activity; inhibits cell proliferation by inducing p53-dependent apoptosis in various human cancer cells (IC50s = 5.4, 51.9, 3.2, 33.9, and 85.4 µM for H460, H1299, A549, HT-29, and WI38 cells, respectively), as well as in xenograft tumors
Storage Temperature:
-20°C
