Eltrombopag
Catalogue number:
CAY13247-1 mg
Supplier:
Size:
1 mg
Product is available in:
£42.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
496775-61-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
442.5
Alternative Names:
3’-[2-[(2z)-1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4h-pyrazol-4-ylidene]hydrazinyl]-2’-hydroxy-[1,1’-biphenyl]-3-carboxylic acid, sb 497115
- Data sheet: View or download
- MSDS: View or download
Product Description:
A thrombopoietin receptor agonist (EC50 = 0.27 µM) and iron chelator; It increases STAT5 phosphorylation in N2C-Tpo cells at 30 µM and p42/44 MAPK phosphorylation at 10 µM; stimulates megakaryocytopoiesis in human primary bone marrow cells; increases platelet production in chimpanzees at 10 mg/kg per day for five days; binds to iron (III) and mobilizes cellular iron and ferritin in H9C2, Huh7, and RINm5F cells
Storage Temperature:
-20°C
