Vps34-IN1
Catalogue number:
CAY17392-1 mg
Supplier:
Size:
1 mg
Product is available in:
£35.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1383716-33-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
425.9
Alternative Names:
1-[[2-[(2-chloro-4-pyridinyl)amino]-4'-(cyclopropylmethyl)[4,5'-bipyrimidin]-2'-yl]amino]-2-methyl-2-propanol, vacuolar protein sorting 34 inhibitor 1, vps34 inhibitor 1
- Data sheet: View or download
- MSDS: View or download
Product Description:
A potent and selective inhibitor of Vps34 (IC50 = 25 nM in vitro); dose-dependently inhibits generation of PtdIns-(3)-p, which is essential to the formation and trafficking of endsomes and autophagosomes, without affecting the ability of class I PI3K to regulate Akt; induces a rapid and pronounced loss of phosphorylation on serum- and glucocorticoid-regulated kinase 3
Storage Temperature:
-20°C
