Pixantrone (maleate)
Catalogue number:
CAY20055-10 mg
Supplier:
Size:
10 mg
Product is available in:
£220.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
144675-97-8
Purity:
≥95%
Formulation:
A crystalline solid
Molecular Weight:
557.5
Alternative Names:
6,9-bis[(2-aminoethyl)amino]-benz[g]isoquinoline-5,10-dione, dimaleate, bbr 2778
- Data sheet: View or download
- MSDS: View or download
Product Description:
A DNA topoisomerase II inhibitor; induces SV40 DNA cleavage in the presence of mouse topoisomerase II; induces DNA single-strand breaks in NCI H187 cells; is cytotoxic to L1210 cells as well as doxorubicin-sensitive and -resistant LoVo cells (IC50 = 0.01, 0.24, and 7.2 µg/ml, respectively); decreases disease severity in a rat model of T. californica AChR immunization-induced myasthenia gravis at 8.12 mg/kg once per week for six weeks
Storage Temperature:
-20°C