PD-1/PD-L1 Inhibitor 1
Catalogue number:
CAY19914-5 mg
Supplier:
Size:
5 mg
Product is available in:
£146.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1675201-83-8
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
475.6
Alternative Names:
(2s)-1-[[2,6-dimethoxy-4-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]phenyl]methyl]-2-piperidinecarboxylic acid, bms-1, programmed cell death 1/programmed cell death-ligand 1 inhibitor 1
- Data sheet: View or download
- MSDS: View or download
Product Description:
A PD-1/PD-L1 interaction inhibitor; inhibits the PD-1/PD-L1 interaction in a TR-FRET assay (IC50 = 6-100 nM); reduces LPS-induced increases in PD-1 levels and apoptosis in MH-S mouse alveolar macrophages at 1 µM; surgical neointimal patching with PD-1/PD-L1-coated patches decreases neointimal thickness and inflammatory cell accumulation in a rat model of patch angioplasty
Storage Temperature:
-20°C
