PQ-10
Catalogue number:
CAY21867-10 mg
Supplier:
Size:
10 mg
Product is available in:
£237.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
927691-21-2
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C22H21N5O3
Molecular Weight:
403.4
Alternative Names:
6,7-dimethoxy-
- MSDS: View or download
Product Description:
A potent and selective inhibitor of phosphodiesterase type 10 (PDE10; Ki = 4 nM); has >38-fold selectivity for PDE10 over a panel of 60 CNS-associated receptors, enzymes, and ion channels in vitro; increases striatal cGMP and CREB phosphorylation in vivo; reduces scopolamine- and MK-801-induced memory deficits in rats; inhibits tumor cell growth with IC50 values of 0.29 and 0.22 mM for HCT116 and SW480 colon cancer cells, respectively
