SGA360
Catalogue number:
CAY21986-10 mg
Supplier:
Size:
10 mg
Product is available in:
£367.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
680611-86-3
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C19H17F3N2O2
Molecular Weight:
362.4
Alternative Names:
3-(2,4-dimethoxy
Product Description:
A selective modulator of AhR; competitively binds AhR (IC50 = 3 µM); represses IL-1β-induced SAA1 gene expression in Huh7 cells; reduces inflammation and decreases the mRNA expression of COX-2, IL-6, IL-1β, SAA3, and IL-10 in wild-type, but not AhR knockout, mice in a model of inflammatory ear edema; reduces acute inflammation in murine models of septic shock, gout, and peritonitis when the high-affinity AhR variant is expressed
