Ipragliflozin
Catalogue number:
CAY22287-250 mg
Supplier:
Size:
250 mg
Product is available in:
£592.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
761423-87-4
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
404.5
Alternative Names:
(1s)-1,5-anhydro-1-c-[3-(benzo[b]thien-2-ylmethyl)-4-fluorophenyl]-d-glucitol, asp1941
- Data sheet: View or download
- MSDS: View or download
Product Description:
A SGLT2 inhibitor (IC50 = 7.4 nM in CHO cells expressing the human cotransporter); selective for SGLT2 over SGLT1, SGLT3, SGLT4, SGLT5, and SGLT6 (IC50s = 1.9, 30.4, 15.9, 0.46, and 10.4 µM, respectively); decreases plasma levels of insulin and glucose in an oral glucose tolerance test in a mouse model of diabetes induced by high-fat diet, STZ, and nicotinamide from 0.1-3 mg/kg; decreases plasma and hepatic IL-6, TNF-α, CCL2, and CRP levels in the same model at 3 mg/kg per day for 28 days
Storage Temperature:
-20°C
