O-Desmethyl Gefitinib
Catalogue number:
CAY22365-5 mg
Supplier:
Size:
5 mg
Product is available in:
£208.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
847949-49-9
Purity:
≥95%
Formulation:
A solid
Molecular Weight:
432.9
Alternative Names:
4-[(3-chloro-4-fluorophenyl)amino]-6-[3-(4-morpholinyl)propoxy]-7-quinazolinol
- Data sheet: View or download
- MSDS: View or download
Product Description:
A major active metabolite of gefitinib in human plasma; inhibits EGFR in subcellular assays similarly to gefitinib (IC50s = 36 and 22 nM, respectively); less active than gefitinib in whole cell assays (IC50s = 760 and 49 nM, respectively); does not reduce tumor growth as well as gefitinib in a LoVo tumor mouse xenograft model
Storage Temperature:
-20°C
