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VX-809

Catalogue number:
CAY22196-1 mg
Supplier:
Size:
1 mg
Product is available in:
  • UK
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£47.00 Estimated delivery Wed 24 Dec
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:

936727-05-8

Purity:

≥98%

Formulation:

A crystalline solid

Molecular Formula:

C24H18F2N2O5

Molecular Weight:

452.4

Alternative Names:

3-[6-[[[1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropyl]carbonyl]amino]-3-methyl-2-pyridinyl]-benzoic acid, lumacaftor, vrt-826809

Product Description:

A F508del-CFTR corrector; enhances F508del-CFTR protein maturation and restores chloride transport function in FRT cells (EC50s = 100 and 500 nM, respectively); increases the amount of F508del-CFTR exiting the endoplasmic reticulum in HEK293 cells; increases chloride and fluid transport in cultured human bronchial epithelial cells isolated from cystic fibrosis patients carrying the F508del-CFTR mutation

CAY22196-1 mg: VX-809
CAY22196-1 mg: VX-809