Doxorubicinol (hydrochloride)
Catalogue number:
CAY22386-5 mg
Supplier:
Size:
5 mg
Product is available in:
£1063.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
Purity:
≥90%
Formulation:
A solid
Molecular Weight:
582
Alternative Names:
(8s,10s)-10-[(3-amino-2,3,6-trideoxy-α-l-lyxo-hexopyranosyl)oxy]-8-(1,2-dihydroxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione, monohydrochloride
- Data sheet: View or download
- MSDS: View or download
Product Description:
A doxorubicin metabolite; formed by NADPH-dependent reduction of the side chain carbonyl group of doxorubicin in human, rabbit, and canine cardiac tissue; inhibits sodium-potassium-dependent ATPase activity (IC50 = 5.40 µg/ml) and ATP-dependent calcium uptake (IC50= 4.5 µg/ml) in canine cardiac muscle; increases resting stress in contracting rabbit cardiac muscle
Storage Temperature:
4°C