5-(Hydroxymethyl)-2’-deoxyuridine
Catalogue number:
CAY23381-10 mg
Supplier:
Size:
10 mg
Product is available in:
£48.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
5116-24-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
258.2
Alternative Names:
α-hydroxy-thymidine
- Data sheet: View or download
- MSDS: View or download
Product Description:
A nucleoside analog; inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 µM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 µM); acts synergistically with 5-FU against HT-29, HCT116, PANC-1, and EKVX cancer cells; inhibits HSV-1 pyrimidine 2’-deoxyribonucleoside kinase (Ki = 3.5 µM) and reduces HSV-1 viral titer to 0.05% of the control at a concentration of 200 µM; a DNA adduct formed in response to oxidative stress
Storage Temperature:
-20°C
