Ambrisentan
Catalogue number:
CAY23669-10 mg
Supplier:
Size:
10 mg
Product is available in:
£239.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
177036-94-1
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
378.4
Alternative Names:
αs-[(4,6-dimethyl-2-pyrimidinyl)oxy]-β-methoxy-β-phenyl-benzenepropanoic acid
- Data sheet: View or download
- MSDS: View or download
Product Description:
A nonpeptide ET-A receptor antagonist (IC50s = 0.251, 0.316, 0.398, 251, and 630 nM for rat preparations of heart, bladder, kidney, lung, and cerebral cortex, respectively); inhibits ET-1-induced contraction of human pulmonary and radial arteries in vitro (Kd = 0.042 and 0.11 µM, respectively); decreases PAH, RVH, and RV peak pressure in a rat model of neonatal hyperoxic lung injury (20 mg/kg per day, s.c.)
Storage Temperature:
-20°C
