(R)-Cetirizine (hydrochloride)
Catalogue number:
CAY23992-100 mg
Supplier:
Size:
100 mg _$$_
Product is available in:
£694.00
Estimated delivery Wed 31 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
130018-87-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
461.8
Alternative Names:
2-[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid, dihydrochloride, levocetirizine
- MSDS: View or download
Product Description:
A selective histamine H1 receptor antagonist; the (R)-enantiomer of cetirizine; binds to the H1 receptor with higher affinity than cetirizine (Kis = 3 and 6 nM, respectively) and is highly selective for H1 over M1-M5 receptors; decreases production of RANTES and eotaxin following antigen stimulation in mouse eosinophils in vitro (MEC = 0.05 µM); dose-dependently decreases histamine-induced nasal rubbing and sneezing in mice (0.01-1% solution)
Storage Temperature:
-20°C