£378.00
Estimated delivery Wed 31 Jul
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
68-88-2
Purity:
≥98%
Formulation:
A solution in ethanol
Molecular Weight:
374.9
Alternative Names:
2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-ethanol, nsc 169188, u.c.b 4492
- Data sheet: View or download
- MSDS: View or download
Product Description:
A histamine H1 receptor antagonist (Ki = 1.9 nM); binds competitively with the H1 receptor inverse agonist mepyramine in polymorphonuclear leukocytes (IC50 = 80 µM); metabolized to cetirizine in vivo; prevents histamine-induced recruitment of rolling leukocytes in rat mesentery post-capillary venules in situ (10 µM); decreases anxiety-like behavior in mice in the elevated plus maze and light-dark exploration test
Storage Temperature:
-20°C