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4759-48-2
≥98%
A crystalline solid
300.4
13-cis-retinoic acid, 13(z)-retinoic acid, 13-cis-vitamin a acid, agn 190013
- Data sheet: View or download
- MSDS: View or download
A retinoid; increases the doubling time and transcription of RARβ mRNA in various human oral squamous cell carcinoma cells at 1 µM; inhibits proliferation of primary human sebocytes (IC50 = 10 µM); decreases triglyceride, stearyl ester, and free fatty acid synthesis and modulates keratin expression in primary human sebocytes at 0.1 µM; reduces chronic rejection damage and decreases mRNA expression of IFN-γ and IL-10 in allografts in chronic Fisher344➛Lewis transplant mice at 2 mg/kg per day; slows rod and cone recovery and prevents light-induced photoreceptor damage in an albino rat model of photoreceptor degeneration at 40 mg/kg
-20°C