2,3-Dimethoxy-5-methyl-p-benzoquinone
Catalogue number:
CAY20504-10 g
Supplier:
Size:
10 g
Product is available in:
£308.00
Estimated delivery Wed 24 Dec
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
605-94-7
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Formula:
C9H10O4
Molecular Weight:
182.2
Alternative Names:
2,3-dimethoxy-
Product Description:
An intermediate in the synthesis of ubiquinones that has anticancer activity; inhibits the growth of SKOV-3, A2780, and A2870/CP70 human ovarian carcinoma cells (IC50s = 26.6, 27.3, and 28.4 µM, respectively); halts the cell cycle at the G2/M phase, increases ROS production, and induces autophagy and apoptosis in SKOV-3 human ovarian carcinoma cells; downregulates the protooncogene HER-2 in vitro; decreases the incidence of tumors and tumor burden in a SKOV-3 mouse xenograft model at 2.5 mg/kg every four days
