18-hydroxy-11-deoxy Corticosterone
Catalogue number:
CAY10007851-1 mg
Supplier:
Size:
1 mg
Product is available in:
£229.00
Estimated delivery Wed 7 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
379-68-0
Formulation:
A solid
Molecular Weight:
346.5
Alternative Names:
18,21-dihydroxy-pregn-4-ene-3,20-dione, 18-hydroxydeoxycorticosterone, 18-oh-doc
- Data sheet: View or download
- MSDS: View or download
Product Description:
A mineralocorticoid secreted by the zona fasciculata of the adrenal gland; biosynthesis is regulated by ACTH as well as angiotensin II, which increases 18-OH-DOC production in isolated human adrenal glomerulosa cells; an intermediate in the metabolism of progesterone; can be formed via conversion of DOC in human SK-MEL188 melanoma cells; can be converted to aldosterone by the capsular portion of rat adrenal glands; increases systolic blood pressure in uninephrectomized saline-drinking rats at 200 µg/rat per day; plasma levels of 18-OH-DOC are elevated in a db/db mouse model of type 2 diabetes
Storage Temperature:
-20°C
