TNF-alpha, Human, mAb T1
Catalogue number:
HM2024-20UG
Supplier:
Size:
20 µg _$$_
Product is available in:
Applications:
Flow cytometry, Functional studies, Immuno assays, Western blot
Immunogen:
BALB/c mice with huTNF, fusion of spleen cells with NSO myeloma cells (ref.1)
- MSDS: View or download
Product Description:
The antibody reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha. The antibody inhibits the biological activity of both forms. It does not react with receptor bound TNF-alpha. It can be a useful tool to discriminate between the membrane form of TNF expressed on producer cells and the proteolytically cleaved, soluble TNF-alpha bound to its cognate cell membrane receptors (TNF-RI and TNF-RII). For this purpose we recommend to use this antibody in combination with the anti-TNF-alpha antibody HM2026, which recognizes soluble, membrane and receptor bound TNF-alpha.
