£252.00
Estimated delivery Fri 2 Aug
Shipping is calculated in checkout
Shipping is calculated in checkout
This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
945614-12-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
556.6
Alternative Names:
n-[3-(1,1-dimethylethyl)-1-(4-methylphenyl)-1h-pyrazol-5-yl]-n'-[[5-fluoro-2-[[1-(2-hydroxyethyl)-1h-indazol-5-yl]oxy]phenyl]methyl]-urea, arry 614
- Data sheet: View or download
- MSDS: View or download
Product Description:
A dual inhibitor of Tie2 and p38 MAPK (IC50s = 1, 26, and 35 nM for Tie2, p38α, and p38β, respectively); inhibits Abl, ARG, FGFR, FLT1, FLT4, Fyn, HCK, LYN, and MINK (IC50s = 4, 10, 28, 47, 42, 41, 26, 25, and 26 nM, respectively); reduces proliferation of KG-1 and KT-1 leukemic cells in vitro
Storage Temperature:
-20°C
