£146.00
Estimated delivery Fri 2 Aug
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
1108-68-5
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
458.6
Alternative Names:
16β-(acetyloxy)-14,15β-epoxy-3β,5β-dihydroxy-bufa-20,22-dienolide, nsc 90326
- Data sheet: View or download
- MSDS: View or download
Product Description:
A steroid glycoside with diverse biological activities; reduces SRC-3 protein levels in MCF-7 breast cancer cells from 10-100 nM; reduces Na+/K+ pump activity, viability, and cell attachment of C7-MDCK cells at 1 µM; reduces expression of EMT markers and migration and invasion of PC3 cells; cytotoxic to A549, H460, and HTB-58 lung cancer cells from 0.1-10 µM; reduces tumor volume and increases survival in an A549 mouse xenograft model at 1 and 5 mg/kg
Storage Temperature:
-20°C