£95.00
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This product is for research use only and is not for human consumption or therapeutic use.
CAS Number:
742112-33-0
Purity:
≥98%
Formulation:
A crystalline solid
Molecular Weight:
460.5
Alternative Names:
2-amino-n-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1h-pyrazol-1-yl]phenyl]-acetamide
- Data sheet: View or download
- MSDS: View or download
Product Description:
An analog of celecoxib that inhibits PDK-1 (IC50 = 5 µM), and therefore Akt activation, with no measurable COX-2 inhibition up to 50 µM; inhibits tumor cell growth (IC50s ~ 1.1 µM) across a panel of 60 cancer cell lines and induces apoptosis of chronic lymphocytic leukemia cells independent of bcl-2 overexpression using both caspase-dependent and independent pathways
Storage Temperature:
-20°C
